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From Lexington
- Take U.S. 52 north to Winston-Salem.
- Take Interstate Business 40 west to the Old Salem exit (5D).
- Turn left on First Street, then left (south) on Liberty Street.
- Continue south 6/10 mile to Academy Street, and turn left into Old Salem.
- Turn right on Main Street at the Single Brothers House.
- Continue 1/10 mile on Main Street, and the Old Salem Tavern is on the right.
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